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KMID : 0360219710120040019
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Journal of the Korean Ophthalmological Society
1971 Volume.12 No. 4 p.19 ~ p.24
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Studies on the Correlation Between the Choroidal Blood Flow and ERG in Rabbits
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Abstract
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The purpose of this paper is to investigate the possible correlation between the choroidal blood flow and the amplitude of the b-wave, in albino rabbits. The following vasoactive drugs were administered intravenously in order to change the blood flow, and the blood flow and the ERG were measured in the dark room after 30 minutes dark adaptation.
Epinephrine (0.5 mg/kg) produced slight reduction in the b-potential only when the blood flow decreased more than 10%.
Pitressin (0.1 m/kg) induced marked degree of blood flow reduction and this changes were always associated with parallel reduction in the b-potential.
Papaverine (2 mg/kg) also produced marked increase in blood flow and marked increase in the bpotential parallel to it.
Hexamethonium bromide (1 mg/kg) produced parallel changes in the blood flow and the b-potential only when the blood flow decreased.
Reserpine (0.2 mg/kg) induced moderate increase in the blood flow and this increase was associated with the increase in the b-potential.
The possible applications of these results in the clinical practice were discussed.
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